Endocrine Abstracts

Introduction: Primary hyperparathyroidism (PHPT) is typically characterized by elevated serum calcium associated with elevated or non-suppressed levels of parathyroid hormone (PTH). These biochemical features are both known to affect the cardiovascular (CV) system. There is a conflicting debate regarding the CV manifestations of PHPT. the aim of our study is to evaluate the cardiovascular profile in patients with PHPT.Methods: We conducted a retrospectiv...

Introduction: The development of the Covid-19 pandemic infection, which started in March 2020 in Tunisia, has impacted all medical specialties. Endocrine care professionals were part of this battle, as many patients with endocrine diseases including primary hyperparathyroidism (PHPT) were also affected by the pandemic. the aim of our study was to evaluate the Impact of the Covid19 pandemic on patients with PHPT.Methods: This is a retrospective descriptiv...

Introduction: Primary hyperparathyroidism (PHPT) is a common endocrine disorder characterized by inappropriate secretion of parathyroid hormone leading to hypercalcemia. The aim of our study is to evaluate the clinical and etiological aspects of PHPT in our series.Methods: This is a retrospective descriptive study including 32 patients followed for PHPT at the endocrinology department of the military hospital of Tunisia between January 2018 and December ...

Introduction: Surgery is the only curative treatment for primary hyperparathyroidism (PHPT). However, some patients may present a persistence or a recurrence after surgical treatment. The aim of our study was to evaluate the therapeutic and evolutive aspects of PHPT after the first surgery.Methods: A retrospective study was conducted at the endocrinology department of military hospital of Tunis including 32 patients diagnosed with PHPT over a period of f...

Introduction: Classification of diabetes is challenging in some cases, especially in the presence of inaugural ketosis with a negative autoimmune laboratory test. The aim of our study is to determine the role of age, body mass index (BMI), and fasting plasma C-peptide (FCP) in the classification of diabetes.Methods: This is a descriptive cross-sectional study that included 51 patients aged between 20 and 65 years hospitalized at the Endocrinology Departm...

Introduction: Papillary Thyroid Carcinoma (PTC) is the most frequent cancer of the thyroid. PTC may rarely coexist with Primary hyperparathyroidism (PHPT). Furthermore, the association of PTC and graves’ disease (GD) has been described and the existence of a link between these entities has long been investigated, but no clear correlation has been established. We report the case of a female patient who suffered from GD, PTC and PHPT.Observation: A 34...

Introduction: Liraglutide is a glucagon-like peptide-1 receptor agonist (GLP-1 RA), approved for management of type 2 diabetes (T2D).Aim: The aim of our study is to evaluate the effectiveness of Liraglutide in controlling blood glucose levels over a period of 6 to 12 months in Tunisian type 2 diabetic patients.Methods: We conducted a prospective descriptive study at the endocrinology-nutrition department of the military hospital of...

Introduction: Liraglutide has been shown to have a positive effect on the glycemic and lipidic profile of diabetic patients. We aimed to assess the metabolic profile in type 2 diabetic patients after 12 weeks of treatment by LiraglutideMethods: This is a prospective study performed at the endocrinology department of the Military Hospital of Tunis. We recruited 22 patients with type 2 diabetes (T2D) treated with insulin and/or oral antidiabetics. Liraglut...

Introduction: Prolactinomas are the most common of functional pituitary tumors. Dopamine agonists are the first line treatment of prolactinomas but have antagonistic effect with antipsychotics (dopamine receptor blockers) used in schizophrenia. The association between these two illnesses is a medical challenge, as the treatment of one disease can exacerbate the symptoms of the other one.Clinical case: We report the case of a 72-year old man, newly diagno...

Introduction: The use of GH treatment in patients with macroadenomas and GH deficiency is of concern to the clinician due to the theoretical stimulation of tumor regrowth by GH substitution. We report the case of an 18-year-old adolescent with a macroprolactinoma causing delayed stature and puberty.Observation : We report the case of an 18-year-oldadolescent who consulted for gynecomastia with delayed stature and puberty. Physical examination displayed a...